[PDF] Undetectable = Untransmittable (U = U) Messaging Increases Uptake of HIV Testing Among Men: Results from a Pilot Cluster Randomized Trial | Semantic Scholar (2024)

Men from high HIV burden communities in Cape Town, South Africa are asked to create a U=U message aimed at increasing HIV testing and ART uptake in men, and co-created, tailored messaging may improve the uptake of HIV services for South African men.

Cocreated tailored messaging may reduce stigma associated with living with HIV and improve the uptake of HIV testing and treatment among South African men.

These trials are the first to rigorously evaluate the impact of U=U messaging on HIV testing uptake, ART initiation and achievement of viral suppression among African men and can shape global HIV testing, treatment and adherence counselling guidelines and practices.

Great knowledge was associated with more positive attitudes towards TasP and interventions providing TasP or U = U information and emerging evidence on interventions delivering information on TasP suggests beneficial impacts on knowledge, stigma, HIV testing, and viral suppression.

Three themes emerged from the analysis: Conflicting beliefs in U = U; (a) Conflicting beliefs in U = U; (b) Use condoms regardless; and (c) Fear of HIV reinfection.

Recent interventions to improve HIV testing uptake in global settings span a breadth of facility- and community-based approaches and should consider supporting linkage to care for newly diagnosed PLWH.

It is argued that understanding the full range of opportunities enabled by viral suppression, including the elimination of transmission risk, could transform adolescents' understanding of living with HIV, incentivise optimal treatment engagement and support and sustain their positive mental health.

Gender-responsive interventions tailored to men’s needs, wants, and voices will facilitate their uptake of HIV prevention services, and help to end the HIV epidemic.

To identify barriers to TasP adoption among some of those most affected by HIV, in-depth qualitative interviews with 62 sexual and gender minority individuals of varying serostatuses identified seven primary barriers.

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The underlying science-based evidence supporting the Undetectable = Untransmittable (U = U) concept is examined and the behavioral, social, and legal implications associated with the acceptance are examined.

This work explored knowledge and acceptance of information around the elimination of HIV transmission risk with ART (U = U) in Kenya with a focus on HIV viral suppression.

There is a need for enhanced education among men about serodiscordance in stable relationships and about the preventive effects of ART in married couples with an HIV-positive female partner.

Being on PrEP, having recent condomless sex with casual partners or a HIV-positive regular partner were independently associated with comfort having condomlesssex.

The low ART uptake, together with men’s more advanced HIV disease at ART initiation, suggested that men experienced barriers in accessing ART despite their willingness to test for HIV, and it is called for widespread targeted HTC campaigns and HIV and ART services for men.

ART initiation during AHI is efficacious and clinicians can monitor for virologic failure after 24 weeks of therapy, as well as investigate viral dynamics and common criteria for treatment success after ART initiation during acute HIV infection (AHI).

Based on the negative impact of food insecurity on morbidity and patterns of healthcare utilization among HIV-infected individuals, policies and programs that address food insecurity should be a critical component of HIV treatment programs worldwide.

Six brief versions of the valid and reliable 10-item Alcohol Use Disorders Identification Test (AUDIT) may potentially replace the full AUDIT in busy HIV care settings in South Africa to identify and manage excessive alcohol use among patients in HIV care setting.

Even though asymptomatic and mild forms of cognitive impairment are prevalent in the population studied, there was no significant association between cognitive impairment and adherence to treatment.

ART has had a dramatic impact on adult mortality in South Africa, but delays in the rollout of ART, especially in the early stages of the ART programme, have contributed to substantial loss of life.

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